3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methylthiophen-2-yl)boronate
3-Methylthiophene-2-boronic acid pinacol ester
CAS: 885692-91-1
Molecular Formula: C11H17BO2S
3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methylthiophen-2-yl)boronate - Names and Identifiers
3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methylthiophen-2-yl)boronate - Physico-chemical Properties
| Molecular Formula | C11H17BO2S |
| Molar Mass | 224.13 |
| Density | 1.06±0.1 g/cm3(Predicted) |
| Melting Point | 57-62°C |
| Boling Point | 305.3±30.0 °C(Predicted) |
| Solubility | soluble in Toluene |
| Appearance | powder to crystal |
| Color | White to Almost white |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methylthiophen-2-yl)boronate - Risk and Safety
| WGK Germany | 3 |
3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-methylthiophen-2-yl)boronate - Introduction
Acid pinacol ester is an organic compound with the chemical formula C11H15BO2S. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: Colorless to light yellow solid.
-Solubility: Soluble in some organic solvents, such as ether, dichloromethane and chloroform.
-Melting point: approximately 40-45°C.
-Stability: relatively stable at room temperature.
Use:
-acid pinacol ester is an important reagent in organic synthesis and is commonly used in copper-catalyzed coupling reactions, such as Suzuki reactions and Sonogashira reactions.
-It is also used in the fields of pharmaceutical and agricultural science, and can be used as an intermediate for the synthesis of biologically active compounds.
Preparation Method:
The preparation of acid pinacol ester is usually carried out by the following steps:
1.3-methyl thiophene and diethyl borate were reacted under certain conditions to generate 3-methyl thiophene -2-diethyl borate.
2. Methylthiophene-2-boronic acid diethyl ester reacts with pyrenol, and 3 is neutralized by acid-base or other methods to obtain acid pinacol ester.
Safety Information:
-the toxicity and danger of pinacol ester is relatively low, but it should still be handled with care.
-Wear appropriate personal protective equipment such as lab gloves and goggles when operating.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-When storing, it should be kept in a dry, cool place, and away from fire and flammable substances.
Nature:
-Appearance: Colorless to light yellow solid.
-Solubility: Soluble in some organic solvents, such as ether, dichloromethane and chloroform.
-Melting point: approximately 40-45°C.
-Stability: relatively stable at room temperature.
Use:
-acid pinacol ester is an important reagent in organic synthesis and is commonly used in copper-catalyzed coupling reactions, such as Suzuki reactions and Sonogashira reactions.
-It is also used in the fields of pharmaceutical and agricultural science, and can be used as an intermediate for the synthesis of biologically active compounds.
Preparation Method:
The preparation of acid pinacol ester is usually carried out by the following steps:
1.3-methyl thiophene and diethyl borate were reacted under certain conditions to generate 3-methyl thiophene -2-diethyl borate.
2. Methylthiophene-2-boronic acid diethyl ester reacts with pyrenol, and 3 is neutralized by acid-base or other methods to obtain acid pinacol ester.
Safety Information:
-the toxicity and danger of pinacol ester is relatively low, but it should still be handled with care.
-Wear appropriate personal protective equipment such as lab gloves and goggles when operating.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-When storing, it should be kept in a dry, cool place, and away from fire and flammable substances.
Last Update：2024-04-10 22:29:15
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Product Name: 3-METHYLTHIOPHENE-2-BORONIC ACID PINACOL ESTER Visit Supplier Webpage Request for quotation
CAS: 885692-91-1
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Mobile: 18021002903
QQ: 3008007409
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CAS: 885692-91-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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